Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
NIDE0052Metallo-beta-lactamase superfamily hydrolase; Function of strongly homologous gene; enzyme. (291 aa)    
Predicted Functional Partners:
alkA
DNA-3-methyladenine glycosylase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
       0.793
yahD
Conserved protein of unknown function, contains Ankyrin repeats; Homologs of previously reported genes of unknown function; 15063798, 8108379.
   
 
 0.775
NIDE3565
Putative Ferredoxin-thioredoxin reductase, catalytic subunit; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
  
     0.615
ycbK
Conserved exported protein of unknown function, DUF882; Homologs of previously reported genes of unknown function; 15802249, 16322447, 16756481, 9841666.
  
    0.555
NIDE1946
Protein of unknown function, putative exoprotein of filamentous haemagglutinin family; No homology to any previously reported sequences; 16339899, 2539596, 7519681, 9724625.
  
     0.542
NIDE0050
Putative Endoribonuclease L-PSP, YjgF-like; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
  
    0.524
NIDE0274
Homologs of previously reported genes of unknown function.
  
     0.495
NIDE0048
Putative Methyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
 
 
   0.490
clpS
ATP-dependent Clp protease adapter protein ClpS; Function of strongly homologous gene; regulator; Belongs to the ClpS family.
  
     0.486
NIDE1742
Putative Multi-domain non-ribosomal peptide synthetase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
   
 
 0.482
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
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