Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
merPPeriplasmic mercury ion binding protein; Involved in mercury resistance. Acts as a mercury scavenger that specifically binds to a mercuric ion in the periplasm and probably passes it to the cytoplasmic mercuric reductase MerA via the mercuric transport protein MerT. (94 aa)    
Predicted Functional Partners:
merT
Mercury ion transport protein; Function of strongly homologous gene; transporter.
 
  
 0.989
merR
Mercuric resistance operon regulatory protein; Function of homologous gene experimentally demonstrated in an other organism; regulator.
 
  
 0.979
copA
Copper-exporting ATPase; Function of strongly homologous gene; transporter.
 
 
 0.970
NIDE0067
Homologs of previously reported genes of unknown function.
 
  
 0.875
arsR
Arsenical resistance operon repressor; Function of homologous gene experimentally demonstrated in an other organism; regulator.
     
 0.832
zitB
Zinc transporter ZitB; Function of homologous gene experimentally demonstrated in an other organism; transporter.
     
 0.829
cutA
Divalent-cation tolerance protein CutA; Function of homologous gene experimentally demonstrated in an other organism; factor.
      
 0.752
ynfA
Conserved membrane protein of unknown function, UPF0060; Homologs of previously reported genes of unknown function.
       0.544
rplN
50S ribosomal protein L14; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family.
    
   0.470
NIDE4168
Putative Glutathione-regulated potassium-efflux system; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.
  
  
 0.462
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
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