Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
NIDE0136Putative Type I restriction endonuclease, R subunit; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (740 aa)    
Predicted Functional Partners:
hsdM
Type I restriction endonuclease, M subunit (modular protein); Function of strongly homologous gene; enzyme.
 
 0.975
NIDE0137
Protein of unknown function, putative Type I restriction endonuclease, S subunit; No homology to any previously reported sequences.
 
 
 0.956
hsdM2
Type I restriction-modification system, methyltransferase subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
 
 0.877
NIDE2624
Putative Type I restriction-modification system, specificity subunit; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
 
 
 0.834
NIDE0138
Conserved protein of unknown function, DUF1016; Homologs of previously reported genes of unknown function; 15972856.
       0.784
NIDE2622
Protein of unknown function; No homology to any previously reported sequences.
  
     0.730
NIDE2503
Putative Type I restriction-modification system, specificity protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor.
 
 
 0.510
NIDE0140
Homologs of previously reported genes of unknown function.
       0.479
NIDE1898
Putative Type I restriction system, N-6 adenine-specific DNA methylase HsdM; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
  
 
 0.466
NIDE2146
Protein of unknown function; No homology to any previously reported sequences.
  
 
 0.466
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
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