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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
otsBTrehalose phosphatase; Removes the phosphate from trehalose 6-phosphate to produce free trehalose. (257 aa)    
Predicted Functional Partners:
otsA1
Alpha,alpha-trehalose-phosphate synthase (UDP-forming); Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
 
 0.999
otsA2
Alpha,alpha-trehalose-phosphate synthase (UDP-forming); Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
 
 0.995
NIDE3904
Glycosyl transferase, group 1; Function of strongly homologous gene; enzyme.
  
 0.939
NIDE0143
Glycoside hydrolase, family 15; Function of strongly homologous gene; enzyme.
 
   
 0.923
pgmB
Beta-phosphoglucomutase hydrolase; Function of strongly homologous gene; enzyme.
   
 0.843
glgP
Glycogen phosphorylase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
   
 
 0.830
glgB
1,4-alpha-glucan branching enzyme; Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position; Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
   
 
 0.801
glgC
Glucose-1-phosphate adenylyltransferase; Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc; Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
      
 0.785
rpoN
RNA polymerase, sigma-54 (sigma N) factor; Function of homologous gene experimentally demonstrated in an other organism; factor.
   
    0.762
NIDE3623
Putative 2,5-diketo-D-gluconic acid reductase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
   
  
 0.712
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
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