NIDE0146 protein (Nitrospira defluvii) - STRING interaction network

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[Homology]

Score

NIDE0146

Appr-1-p processing enzyme family protein; Function of strongly homologous gene; enzyme. (161 aa)

Predicted Functional Partners:

rplX

0.737

rplK

0.735

rplC

0.717

rplB

0.717

rplM

0.697

rplU

0.694

NIDE1142

0.649

NIDE1440

0.649

rplN

0.576

rplP

0.542

Your Current Organism:

Nitrospira defluvii

NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
NIDE0146	NIDE1142	NIDE0146	NIDE1142	Appr-1-p processing enzyme family protein; Function of strongly homologous gene; enzyme.	Putative Muconate cycloisomerase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.	0.649
NIDE0146	NIDE1440	NIDE0146	NIDE1440	Appr-1-p processing enzyme family protein; Function of strongly homologous gene; enzyme.	Putative Muconate cycloisomerase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the mandelate racemase/muconate lactonizing enzyme family.	0.649
NIDE0146	rplB	NIDE0146	NIDE1314	Appr-1-p processing enzyme family protein; Function of strongly homologous gene; enzyme.	50S ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.	0.717
NIDE0146	rplC	NIDE0146	NIDE1311	Appr-1-p processing enzyme family protein; Function of strongly homologous gene; enzyme.	50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family.	0.717
NIDE0146	rplK	NIDE0146	NIDE1300	Appr-1-p processing enzyme family protein; Function of strongly homologous gene; enzyme.	50S ribosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.	0.735
NIDE0146	rplM	NIDE0146	NIDE2753	Appr-1-p processing enzyme family protein; Function of strongly homologous gene; enzyme.	50S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.	0.697
NIDE0146	rplN	NIDE0146	NIDE1321	Appr-1-p processing enzyme family protein; Function of strongly homologous gene; enzyme.	50S ribosomal protein L14; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family.	0.576
NIDE0146	rplP	NIDE0146	NIDE1318	Appr-1-p processing enzyme family protein; Function of strongly homologous gene; enzyme.	50S ribosomal protein L16; Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs; Belongs to the universal ribosomal protein uL16 family.	0.542
NIDE0146	rplU	NIDE0146	NIDE1102	Appr-1-p processing enzyme family protein; Function of strongly homologous gene; enzyme.	50S ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.	0.694
NIDE0146	rplX	NIDE0146	NIDE1322	Appr-1-p processing enzyme family protein; Function of strongly homologous gene; enzyme.	50S ribosomal protein L24; One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.	0.737
NIDE1142	NIDE0146	NIDE1142	NIDE0146	Putative Muconate cycloisomerase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.	Appr-1-p processing enzyme family protein; Function of strongly homologous gene; enzyme.	0.649
NIDE1440	NIDE0146	NIDE1440	NIDE0146	Putative Muconate cycloisomerase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the mandelate racemase/muconate lactonizing enzyme family.	Appr-1-p processing enzyme family protein; Function of strongly homologous gene; enzyme.	0.649
rplB	NIDE0146	NIDE1314	NIDE0146	50S ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.	Appr-1-p processing enzyme family protein; Function of strongly homologous gene; enzyme.	0.717
rplB	rplC	NIDE1314	NIDE1311	50S ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.	50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family.	0.999
rplB	rplK	NIDE1314	NIDE1300	50S ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.	50S ribosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.	0.997
rplB	rplM	NIDE1314	NIDE2753	50S ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.	50S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.	0.997
rplB	rplN	NIDE1314	NIDE1321	50S ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.	50S ribosomal protein L14; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family.	0.998
rplB	rplP	NIDE1314	NIDE1318	50S ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.	50S ribosomal protein L16; Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs; Belongs to the universal ribosomal protein uL16 family.	0.999
rplB	rplU	NIDE1314	NIDE1102	50S ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.	50S ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.	0.985
rplB	rplX	NIDE1314	NIDE1322	50S ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.	50S ribosomal protein L24; One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.	0.995