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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NIDE0153Putative Mechanosensitive ion channel, transmembrane region (fragment); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter. (178 aa)    
Predicted Functional Partners:
mscS
Small-conductance mechanosensitive channel; Function of homologous gene experimentally demonstrated in an other organism; transporter.
 
  
 0.743
NIDE3861
Homologs of previously reported genes of unknown function.
   
    0.654
gcvP
Glycine dehydrogenase, glycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.
   
    0.545
NIDE0152
Protein of unknown function; No homology to any previously reported sequences.
       0.536
NIDE3262
Putative Small-conductance mechanosensitive channel with cAMP-binding domain (modular protein); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter.
 
  
 0.535
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
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