Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
suhBInositol-phosphate phosphatase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the inositol monophosphatase superfamily. (273 aa)    
Predicted Functional Partners:
NIDE4351
Putative Inositol-phosphate phosphatase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
 
  
 
0.967
NIDE0736
Putative sugar nucleotidyltransferase and phosphatidyltransferase (bifunctional enzyme); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
  
 
 0.911
ppnK
NAD(+) kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
 
    0.905
ubiA
4-hydroxybenzoate octaprenyltransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the UbiA prenyltransferase family.
     
 0.807
hslU
Heat shock protein HslVU, ATPase subunit; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
      
 0.795
phnW
2-aminoethylphosphonate aminotransferase; Function of strongly homologous gene; enzyme.
      
 0.793
trxB
Thioredoxin-disulfide reductase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
     
 0.778
ppa
Inorganic pyrophosphatase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
      
 0.778
nusA
Transcription termination factor NusA; Participates in both transcription termination and antitermination.
   
   0.761
rpoC
DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.728
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
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