Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
phrDeoxyribodipyrimidine photolyase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the DNA photolyase family. (481 aa)    
Predicted Functional Partners:
NIDE0204
Homologs of previously reported genes of unknown function.
  
  
 0.981
NIDE0618
BLUF domain protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative receptor.
  
   
 0.843
lexA
LexA repressor; Represses a number of genes involved in the response to DNA damage (SOS response).
      
 0.823
recA
Recombinase RecA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
      
 0.779
NIDE0202
Membrane protein of unknown function; No homology to any previously reported sequences.
       0.773
NIDE0190
Putative Regulatory protein, MerR family, Cobalamin B12-binding; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator.
 
  
 0.763
ung
Uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
 
      0.697
NIDE0200
Exported protein of unknown function, PDZ domain; No homology to any previously reported sequences; 10887205, 8674113, 9041651, 9204764, 9382826.
       0.692
yfcH
Conserved protein of unknown function, NAD(P)-binding Rossmann-fold domain; Homologs of previously reported genes of unknown function.
  
    0.651
NIDE0201
Protein of unknown function; No homology to any previously reported sequences.
       0.640
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
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