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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pepALeucyl aminopeptidase; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides. (506 aa)    
Predicted Functional Partners:
NIDE4085
Putative Peptidase M; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
   
 0.923
nagZ
Beta-N-acetylglucosaminidase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
    
 0.908
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
 
 0.840
cysK
Cysteine synthase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
   
 0.839
aspC
Aspartate aminotransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
   
  0.815
rlp
Ribulose bisphosphate carboxylase-like protein (RuBisCO type IV-like protein); Function of strongly homologous gene; enzyme.
      
 0.691
czcA
Cation efflux system protein CzcA; Function of strongly homologous gene; transporter; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
      
 0.682
czcA-2
Heavy metal efflux pump, CzcA family; Function of strongly homologous gene; transporter; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
      
 0.682
czcA-3
Cation efflux system protein CzcA; Function of strongly homologous gene; transporter; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
      
 0.682
nirK
Copper-containing nitrite reductase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
      
 0.657
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
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