Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
NIDE0271Sigma-54 dependent response regulator; Function of strongly homologous gene; regulator. (598 aa)    
Predicted Functional Partners:
NIDE0273
Conserved protein of unknown function, small GTP-binding protein; Homologs of previously reported genes of unknown function; 11099382, 12163169, 12384139, 12728271, 17143896.
       0.786
rpoN
RNA polymerase, sigma-54 (sigma N) factor; Function of homologous gene experimentally demonstrated in an other organism; factor.
 
   
 0.766
NIDE0274
Homologs of previously reported genes of unknown function.
  
    0.758
NIDE0270
Protein of unknown function, putative transcriptional regulator; No homology to any previously reported sequences.
   
   0.661
NIDE0269
Protein of unknown function; No homology to any previously reported sequences.
       0.508
NIDE0275
Homologs of previously reported genes of unknown function.
       0.498
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
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