Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
NIDE0273Conserved protein of unknown function, small GTP-binding protein; Homologs of previously reported genes of unknown function; 11099382, 12163169, 12384139, 12728271, 17143896. (178 aa)    
Predicted Functional Partners:
NIDE0274
Homologs of previously reported genes of unknown function.
 
     0.945
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
   
 0.846
NIDE0271
Sigma-54 dependent response regulator; Function of strongly homologous gene; regulator.
       0.786
NIDE3602
Exported protein of unknown function, contains Ankyrin repeats; No homology to any previously reported sequences; 8108379.
 
 0.742
pgk
Phosphoglycerate kinase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the phosphoglycerate kinase family.
  
 
   0.739
yahD
Conserved protein of unknown function, contains Ankyrin repeats; Homologs of previously reported genes of unknown function; 15063798, 8108379.
 
 0.736
NIDE0308
Protein of unknown function, contains Ankyrin and Tetratricopeptide repeats; No homology to any previously reported sequences; 14659697, 7667876, 8108379, 9482716.
  
 0.703
NIDE1946
Protein of unknown function, putative exoprotein of filamentous haemagglutinin family; No homology to any previously reported sequences; 16339899, 2539596, 7519681, 9724625.
  
     0.662
NIDE0270
Protein of unknown function, putative transcriptional regulator; No homology to any previously reported sequences.
       0.651
NIDE0550
Protein of unknown function, DUF928; No homology to any previously reported sequences.
  
     0.629
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
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