STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mscSSmall-conductance mechanosensitive channel; Function of homologous gene experimentally demonstrated in an other organism; transporter. (266 aa)    
Predicted Functional Partners:
NIDE0277
Protein of unknown function; No homology to any previously reported sequences; 8866482.
  
    0.746
NIDE0153
Putative Mechanosensitive ion channel, transmembrane region (fragment); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter.
 
  
 0.744
alkA
DNA-3-methyladenine glycosylase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
      
 0.733
udgA
Uracil-DNA glycosylase; Function of strongly homologous gene; enzyme.
      
 0.733
ppa
Inorganic pyrophosphatase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
      
 0.733
speE
Putative Spermidine synthase modulated with MFS-type transporter; Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
      
 0.732
uvrA
Excinuclease ABC, subunit A; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.
      
 0.627
cobS
Cobalamin synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family.
      
 0.627
uvrA-2
Excinuclease ABC, subunit A; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.
      
 0.627
NIDE3403
Conserved membrane protein of unknown function, MarC-related; Homologs of previously reported genes of unknown function; 8383113.
 
    0.537
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.