STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NIDE0293Putative DNA-binding domain protein, Excisionase family (modular protein); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; extrachromosomal origin. (108 aa)    
Predicted Functional Partners:
int
Phage integrase; Function of strongly homologous gene; enzyme; Belongs to the 'phage' integrase family.
       0.774
NIDE0292
Protein of unknown function; No homology to any previously reported sequences.
       0.673
xerC
Tyrosine recombinase xerC; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.
       0.432
trmFO
tRNA uridine 5-carboxymethylaminomethyl modification enzyme gid; Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs; Belongs to the MnmG family. TrmFO subfamily.
       0.431
hslV
Heat shock protein HslUV, peptidase component; Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.
       0.431
NIDE1987
Conserved protein of unknown function, Rhs element Vgr protein family; Homologs of previously reported genes of unknown function; 16763151, 9696756, 19284603.
   
    0.430
hslU
Heat shock protein HslVU, ATPase subunit; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
       0.419
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.