| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| NIDE0313 | gcvP | NIDE0313 | NIDE0312 | Exported protein of unknown function; No homology to any previously reported sequences. | Glycine dehydrogenase, glycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.773 |
| NIDE0313 | rbsK | NIDE0313 | NIDE0315 | Exported protein of unknown function; No homology to any previously reported sequences. | Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. | 0.664 |
| NIDE0313 | rih | NIDE0313 | NIDE0314 | Exported protein of unknown function; No homology to any previously reported sequences. | Inosine-uridine preferring nucleoside hydrolase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.664 |
| NIDE4241 | apt | NIDE4241 | NIDE1247 | HAD-like hydrolase, putative purine nucleotidase; Function of strongly homologous gene; enzyme. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.905 |
| NIDE4241 | hpt | NIDE4241 | NIDE2738 | HAD-like hydrolase, putative purine nucleotidase; Function of strongly homologous gene; enzyme. | Hypoxanthine phosphoribosyltransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.900 |
| NIDE4241 | rih | NIDE4241 | NIDE0314 | HAD-like hydrolase, putative purine nucleotidase; Function of strongly homologous gene; enzyme. | Inosine-uridine preferring nucleoside hydrolase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.905 |
| NIDE4241 | surE | NIDE4241 | NIDE4107 | HAD-like hydrolase, putative purine nucleotidase; Function of strongly homologous gene; enzyme. | 5'-nucleotidase SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.909 |
| apt | NIDE4241 | NIDE1247 | NIDE4241 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | HAD-like hydrolase, putative purine nucleotidase; Function of strongly homologous gene; enzyme. | 0.905 |
| apt | hpt | NIDE1247 | NIDE2738 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Hypoxanthine phosphoribosyltransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.929 |
| apt | polA | NIDE1247 | NIDE4158 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.490 |
| apt | rbsK | NIDE1247 | NIDE0315 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. | 0.409 |
| apt | rih | NIDE1247 | NIDE0314 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Inosine-uridine preferring nucleoside hydrolase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.915 |
| apt | surE | NIDE1247 | NIDE4107 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 5'-nucleotidase SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.920 |
| gcvP | NIDE0313 | NIDE0312 | NIDE0313 | Glycine dehydrogenase, glycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | Exported protein of unknown function; No homology to any previously reported sequences. | 0.773 |
| gcvP | polA | NIDE0312 | NIDE4158 | Glycine dehydrogenase, glycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.480 |
| gcvP | rbsK | NIDE0312 | NIDE0315 | Glycine dehydrogenase, glycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. | 0.779 |
| gcvP | rih | NIDE0312 | NIDE0314 | Glycine dehydrogenase, glycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | Inosine-uridine preferring nucleoside hydrolase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.664 |
| hpt | NIDE4241 | NIDE2738 | NIDE4241 | Hypoxanthine phosphoribosyltransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | HAD-like hydrolase, putative purine nucleotidase; Function of strongly homologous gene; enzyme. | 0.900 |
| hpt | apt | NIDE2738 | NIDE1247 | Hypoxanthine phosphoribosyltransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.929 |
| hpt | polA | NIDE2738 | NIDE4158 | Hypoxanthine phosphoribosyltransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.641 |
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