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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rpiARibose-5-phosphate isomerase A; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate. (238 aa)    
Predicted Functional Partners:
deoB
Phosphopentomutase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
  
 
 0.966
rpe
D-ribulose-5-phosphate 3-epimerase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the ribulose-phosphate 3-epimerase family.
  
 0.948
rbsK
Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
   
 0.943
tktA
Transketolase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
   
 0.932
pgm
Phosphoglucomutase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
  
 
 0.925
prsA
Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
  
 
 0.923
gnd
6-phosphogluconate dehydrogenase (decarboxylating); Function of homologous gene experimentally demonstrated in an other organism; enzyme.
    
 0.921
manB/pgm
Bifunctional Phosphoglucomutase/Phosphomannomutase; Function of strongly homologous gene; enzyme.
    
 0.915
pgl
6-phosphogluconolactonase; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.
 
  
 0.858
glk
Glucokinase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the bacterial glucokinase family.
     
 0.855
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
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