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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pgl6-phosphogluconolactonase; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate. (253 aa)    
Predicted Functional Partners:
zwf1
Glucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone.
 
 0.999
zwf2
Glucose-6-phosphate dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone.
 
 0.999
gnd
6-phosphogluconate dehydrogenase (decarboxylating); Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
  
 0.970
gntK
Gluconate kinase (fragment); Function of strongly homologous gene; enzyme.
   
 0.930
glk
Glucokinase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the bacterial glucokinase family.
 
  
 0.899
NIDE0356
Putative Glucose-6-phosphate isomerase (modular protein); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the GPI family.
 
 
 0.895
rpiA
Ribose-5-phosphate isomerase A; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
 
  
 0.858
hemC
Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
 
    
 0.744
dnaE
DNA polymerase III, alpha subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
   
    0.670
dnaE2
DNA polymerase III, alpha subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
   
    0.670
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
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