Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
parAChromosomal partitioning ATPase ParA; Function of strongly homologous gene; enzyme. (258 aa)    
Predicted Functional Partners:
parB
Chromosomal partitioning protein ParB; Function of strongly homologous gene; enzyme; Belongs to the ParB family.
 
 0.998
NIDE0092
Site-specific DNA-methyltransferase N-4/N-6 (phage related); Function of strongly homologous gene; enzyme; Belongs to the N(4)/N(6)-methyltransferase family.
  
 
 0.859
NIDE0093
Site-specific DNA-methyltransferase N-4/N-6 (phage related); Function of strongly homologous gene; enzyme; Belongs to the N(4)/N(6)-methyltransferase family.
  
 
 0.859
NIDE0883
Putative Succinoglycan biosynthesis protein ExoA; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
  
 
 0.811
NIDE2864
Glycosyl transferase, group 2; Function of strongly homologous gene; enzyme.
  
 
 0.811
gidB
Methyltransferase GidB; Specifically methylates the N7 position of a guanine in 16S rRNA; Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
  
  
 0.797
ftsZ
Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
  
  
 0.651
oxaA
Inner-membrane protein insertion factor OxaA; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.
 
   
 0.592
ligA
DNA ligase (NAD(+)); DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.
  
    0.590
ftsK
DNA translocase FtsK; Function of strongly homologous gene; enzyme.
  
  
 0.588
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
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