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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
parAChromosomal partitioning ATPase ParA; Function of strongly homologous gene; enzyme. (258 aa)    
Predicted Functional Partners:
parB
Chromosomal partitioning protein ParB; Function of strongly homologous gene; enzyme; Belongs to the ParB family.
 
 0.998
NIDE0092
Site-specific DNA-methyltransferase N-4/N-6 (phage related); Function of strongly homologous gene; enzyme; Belongs to the N(4)/N(6)-methyltransferase family.
  
 
 0.865
NIDE0093
Site-specific DNA-methyltransferase N-4/N-6 (phage related); Function of strongly homologous gene; enzyme; Belongs to the N(4)/N(6)-methyltransferase family.
  
 
 0.865
NIDE2671
Putative Vitamin B12 transporter BtuB precursor; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter.
    
 
 0.833
gidB
Methyltransferase GidB; Specifically methylates the N7 position of a guanine in 16S rRNA; Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
  
  
 0.800
oxaA
Inner-membrane protein insertion factor OxaA; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.
 
   
 0.613
ftsZ
Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
  
  
 0.591
dnaA
Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family.
 
 
 0.582
ftsK
DNA translocase FtsK; Function of strongly homologous gene; enzyme.
  
  
 0.578
NIDE0366
Conserved protein of unknown function, DUF583; Homologs of previously reported genes of unknown function.
     
 0.574
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
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