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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mntBManganese transport system, ATPase component; Function of strongly homologous gene; enzyme. (259 aa)    
Predicted Functional Partners:
mntC
Manganese transport system, permease component; Function of strongly homologous gene; transporter.
 
 0.998
NIDE0385
Putative Manganese transport system, periplasmic binding component; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; lipoprotein; Belongs to the bacterial solute-binding protein 9 family.
 
  
 0.992
btuC
Vitamin B12 import system, permease protein BtuC; Function of strongly homologous gene; transporter; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
 
   
 0.688
NIDE0387
Protein of unknown function; No homology to any previously reported sequences.
       0.499
anmK
Anhydro-N-acetylmuramic acid kinase; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family.
       0.498
fur
Ferric uptake regulation protein; Function of strongly homologous gene; regulator; Belongs to the Fur family.
  
  
 0.455
fur2
Ferric uptake regulation protein Fur; Function of homologous gene experimentally demonstrated in an other organism; regulator; Belongs to the Fur family.
  
  
 0.455
perR
Peroxide-responsive repressor PerR; Function of strongly homologous gene; regulator; Belongs to the Fur family.
  
  
 0.455
NIDE2334
Protein of unknown function, putative Glycosyl transferase; No homology to any previously reported sequences; 9334165.
     
 0.419
dnaJ
Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]
 
 
 
 0.408
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
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