Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
mntBManganese transport system, ATPase component; Function of strongly homologous gene; enzyme. (259 aa)    
Predicted Functional Partners:
mntC
Manganese transport system, permease component; Function of strongly homologous gene; transporter.
 
 0.998
NIDE0385
Putative Manganese transport system, periplasmic binding component; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; lipoprotein; Belongs to the bacterial solute-binding protein 9 family.
 
  
 0.993
btuC
Vitamin B12 import system, permease protein BtuC; Function of strongly homologous gene; transporter; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
 
   
 0.687
NIDE0387
Protein of unknown function; No homology to any previously reported sequences.
       0.489
anmK
Anhydro-N-acetylmuramic acid kinase; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family.
       0.473
fur
Ferric uptake regulation protein; Function of strongly homologous gene; regulator; Belongs to the Fur family.
  
  
 0.462
fur2
Ferric uptake regulation protein Fur; Function of homologous gene experimentally demonstrated in an other organism; regulator; Belongs to the Fur family.
  
  
 0.462
perR
Peroxide-responsive repressor PerR; Function of strongly homologous gene; regulator; Belongs to the Fur family.
  
  
 0.462
NIDE2334
Protein of unknown function, putative Glycosyl transferase; No homology to any previously reported sequences; 9334165.
     
 0.419
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.