Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
hupATranscriptional dual regulator HU-alpha; Function of homologous gene experimentally demonstrated in an other organism; regulator; Belongs to the bacterial histone-like protein family. (90 aa)    
Predicted Functional Partners:
ihfA
Integration host factor, alpha subunit; Function of homologous gene experimentally demonstrated in an other organism; factor; Belongs to the bacterial histone-like protein family.
  
     0.774
rplJL
Fused 50S ribosomal proteins L10 and L7/L12 (modular protein); Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation; Belongs to the bacterial ribosomal protein bL12 family.
  
  
 0.737
NIDE0405
Protein of unknown function, putative transcriptional regulator; No homology to any previously reported sequences; 11183780, 11532124, 1619650, 1986310, 9738943.
     
 0.653
rpsT
30S ribosomal protein S20; Binds directly to 16S ribosomal RNA.
  
  
 0.633
rplS
50S ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
  
   0.618
cspB
Cold shock protein modulated with ribosomal subunit interface-like protein; Function of strongly homologous gene; factor.
  
 
 0.582
rpmI
50S ribosomal protein L35; Function of homologous gene experimentally demonstrated in an other organism; structure; Belongs to the bacterial ribosomal protein bL35 family.
  
    0.537
rpsO
30S ribosomal protein S15; Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
   
  
 0.529
infC
Translation initiation factor IF-3; IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
  
  
 0.476
pheA
P-protein, bifunctional chorismate mutase/prephenate dehydratase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
     
 0.471
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
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