Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Experiments
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[Homology]
Score
NIDE0405Protein of unknown function, putative transcriptional regulator; No homology to any previously reported sequences; 11183780, 11532124, 1619650, 1986310, 9738943. (196 aa)    
Predicted Functional Partners:
NIDE0947
Putative transmembrane signal transduction receptor and sigma-54 dependent response regulator; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator.
     
  0.900
NIDE0618
BLUF domain protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative receptor.
    
 
 0.796
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
   
   0.748
hupA
Transcriptional dual regulator HU-alpha; Function of homologous gene experimentally demonstrated in an other organism; regulator; Belongs to the bacterial histone-like protein family.
     
 0.653
rpsU
30S ribosomal protein S21; Function of homologous gene experimentally demonstrated in an other organism; structure; Belongs to the bacterial ribosomal protein bS21 family.
 
    0.653
NIDE3957
Putative tRNA-dihydrouridine synthase; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family.
  
  
 0.596
rpsJ
30S ribosomal protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family.
   
    0.571
rpsO
30S ribosomal protein S15; Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
   
    0.568
rplM
50S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.
   
    0.560
rpsI
30S ribosomal protein S9; Function of homologous gene experimentally demonstrated in an other organism; structure; Belongs to the universal ribosomal protein uS9 family.
   
    0.484
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
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