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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NIDE0405Protein of unknown function, putative transcriptional regulator; No homology to any previously reported sequences; 11183780, 11532124, 1619650, 1986310, 9738943. (196 aa)    
Predicted Functional Partners:
NIDE0947
Putative transmembrane signal transduction receptor and sigma-54 dependent response regulator; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator.
     
 0.908
NIDE0618
BLUF domain protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative receptor.
    
 
 0.886
NIDE3957
Putative tRNA-dihydrouridine synthase; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family.
  
  
 0.841
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
   
   0.831
hupA
Transcriptional dual regulator HU-alpha; Function of homologous gene experimentally demonstrated in an other organism; regulator; Belongs to the bacterial histone-like protein family.
     
 0.657
rpsU
30S ribosomal protein S21; Function of homologous gene experimentally demonstrated in an other organism; structure; Belongs to the bacterial ribosomal protein bS21 family.
 
    0.611
rplM
50S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.
   
    0.524
rpsI
30S ribosomal protein S9; Function of homologous gene experimentally demonstrated in an other organism; structure; Belongs to the universal ribosomal protein uS9 family.
   
    0.521
typA
GTP-binding protein TypA; Function of homologous gene experimentally demonstrated in an other organism; factor.
   
  
 0.518
NIDE0281
Putative RNA polymerase-binding protein DksA; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor.
  
   
 0.487
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.