trpD protein (Nitrospira defluvii) - STRING interaction network

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Score

trpD

Anthranilate phosphoribosyltransferase; Function of strongly homologous gene; enzyme. (355 aa)

Predicted Functional Partners:

trpE

0.998

trpF

0.995

trpG

0.993

pabB

0.988

trpC

0.964

trpA

0.956

trpB

0.955

trpD-2

0.923

cysD

0.767

cysNC

0.760

Your Current Organism:

Nitrospira defluvii

NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
cysD	cysNC	NIDE0410	NIDE0411	Sulfate adenylyltransferase, subunit 2; Function of homologous gene experimentally demonstrated in an other organism; enzyme.	Sulfate adenylyltransferase, subunit 1, and adenylylsulfate kinase (bifunctional enzyme); Function of strongly homologous gene; enzyme.	0.999
cysD	trpD	NIDE0410	NIDE0409	Sulfate adenylyltransferase, subunit 2; Function of homologous gene experimentally demonstrated in an other organism; enzyme.	Anthranilate phosphoribosyltransferase; Function of strongly homologous gene; enzyme.	0.767
cysNC	cysD	NIDE0411	NIDE0410	Sulfate adenylyltransferase, subunit 1, and adenylylsulfate kinase (bifunctional enzyme); Function of strongly homologous gene; enzyme.	Sulfate adenylyltransferase, subunit 2; Function of homologous gene experimentally demonstrated in an other organism; enzyme.	0.999
cysNC	trpD	NIDE0411	NIDE0409	Sulfate adenylyltransferase, subunit 1, and adenylylsulfate kinase (bifunctional enzyme); Function of strongly homologous gene; enzyme.	Anthranilate phosphoribosyltransferase; Function of strongly homologous gene; enzyme.	0.760
cysNC	trpD-2	NIDE0411	NIDE2042	Sulfate adenylyltransferase, subunit 1, and adenylylsulfate kinase (bifunctional enzyme); Function of strongly homologous gene; enzyme.	Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA).	0.438
pabB	trpA	NIDE3736	NIDE2047	Aminodeoxychorismate synthase, component I; Function of homologous gene experimentally demonstrated in an other organism; enzyme.	Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.	0.939
pabB	trpB	NIDE3736	NIDE2046	Aminodeoxychorismate synthase, component I; Function of homologous gene experimentally demonstrated in an other organism; enzyme.	Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.	0.890
pabB	trpC	NIDE3736	NIDE2043	Aminodeoxychorismate synthase, component I; Function of homologous gene experimentally demonstrated in an other organism; enzyme.	Indole-3-glycerol phosphate synthase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the TrpC family.	0.995
pabB	trpD	NIDE3736	NIDE0409	Aminodeoxychorismate synthase, component I; Function of homologous gene experimentally demonstrated in an other organism; enzyme.	Anthranilate phosphoribosyltransferase; Function of strongly homologous gene; enzyme.	0.988
pabB	trpD-2	NIDE3736	NIDE2042	Aminodeoxychorismate synthase, component I; Function of homologous gene experimentally demonstrated in an other organism; enzyme.	Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA).	0.991
pabB	trpE	NIDE3736	NIDE2040	Aminodeoxychorismate synthase, component I; Function of homologous gene experimentally demonstrated in an other organism; enzyme.	Anthranilate synthase, component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concent [...]	0.820
pabB	trpF	NIDE3736	NIDE2045	Aminodeoxychorismate synthase, component I; Function of homologous gene experimentally demonstrated in an other organism; enzyme.	N-(5'-phosphoribosyl)anthranilate isomerase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the TrpF family.	0.941
pabB	trpG	NIDE3736	NIDE2041	Aminodeoxychorismate synthase, component I; Function of homologous gene experimentally demonstrated in an other organism; enzyme.	Anthranilate synthase, component II; Function of homologous gene experimentally demonstrated in an other organism; enzyme.	0.999
trpA	pabB	NIDE2047	NIDE3736	Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.	Aminodeoxychorismate synthase, component I; Function of homologous gene experimentally demonstrated in an other organism; enzyme.	0.939
trpA	trpB	NIDE2047	NIDE2046	Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.	Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.	0.999
trpA	trpC	NIDE2047	NIDE2043	Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.	Indole-3-glycerol phosphate synthase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the TrpC family.	0.999
trpA	trpD	NIDE2047	NIDE0409	Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.	Anthranilate phosphoribosyltransferase; Function of strongly homologous gene; enzyme.	0.956
trpA	trpD-2	NIDE2047	NIDE2042	Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.	Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA).	0.979
trpA	trpE	NIDE2047	NIDE2040	Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.	Anthranilate synthase, component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concent [...]	0.953
trpA	trpF	NIDE2047	NIDE2045	Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.	N-(5'-phosphoribosyl)anthranilate isomerase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the TrpF family.	0.988