tyrA protein (Nitrospira defluvii) - STRING interaction network

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[Homology]

Score

tyrA

Prephenate dehydrogenase; Function of strongly homologous gene; enzyme. (298 aa)

Predicted Functional Partners:

aroA

0.997

hisC

0.995

pheA

0.991

cmk

0.980

aspC

0.914

aroF

0.848

aroC

0.831

cobD

0.798

fleR

0.795

apt

0.778

Your Current Organism:

Nitrospira defluvii

NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
apt	tyrA	NIDE1247	NIDE0422	Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.	Prephenate dehydrogenase; Function of strongly homologous gene; enzyme.	0.778
aroA	aroC	NIDE0423	NIDE1426	3-phosphoshikimate-1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.	Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.	0.995
aroA	aroF	NIDE0423	NIDE0421	3-phosphoshikimate-1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.	3-deoxy-7-phosphoheptulonate synthase; Function of strongly homologous gene; enzyme.	0.905
aroA	cmk	NIDE0423	NIDE0424	3-phosphoshikimate-1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.	Cytidylate kinase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.	0.981
aroA	cobD	NIDE0423	NIDE2661	3-phosphoshikimate-1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.	Threonine-phosphate decarboxylase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.	0.474
aroA	hisC	NIDE0423	NIDE0420	3-phosphoshikimate-1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.	Histidinol-phosphate aminotransferase; Function of strongly homologous gene; enzyme; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.	0.754
aroA	pheA	NIDE0423	NIDE0419	3-phosphoshikimate-1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.	P-protein, bifunctional chorismate mutase/prephenate dehydratase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.	0.969
aroA	tyrA	NIDE0423	NIDE0422	3-phosphoshikimate-1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.	Prephenate dehydrogenase; Function of strongly homologous gene; enzyme.	0.997
aroC	aroA	NIDE1426	NIDE0423	Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.	3-phosphoshikimate-1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.	0.995
aroC	aroF	NIDE1426	NIDE0421	Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.	3-deoxy-7-phosphoheptulonate synthase; Function of strongly homologous gene; enzyme.	0.629
aroC	cobD	NIDE1426	NIDE2661	Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.	Threonine-phosphate decarboxylase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.	0.659
aroC	hisC	NIDE1426	NIDE0420	Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.	Histidinol-phosphate aminotransferase; Function of strongly homologous gene; enzyme; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.	0.659
aroC	pheA	NIDE1426	NIDE0419	Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.	P-protein, bifunctional chorismate mutase/prephenate dehydratase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.	0.987
aroC	tyrA	NIDE1426	NIDE0422	Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.	Prephenate dehydrogenase; Function of strongly homologous gene; enzyme.	0.831
aroF	aroA	NIDE0421	NIDE0423	3-deoxy-7-phosphoheptulonate synthase; Function of strongly homologous gene; enzyme.	3-phosphoshikimate-1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.	0.905
aroF	aroC	NIDE0421	NIDE1426	3-deoxy-7-phosphoheptulonate synthase; Function of strongly homologous gene; enzyme.	Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.	0.629
aroF	cmk	NIDE0421	NIDE0424	3-deoxy-7-phosphoheptulonate synthase; Function of strongly homologous gene; enzyme.	Cytidylate kinase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.	0.643
aroF	hisC	NIDE0421	NIDE0420	3-deoxy-7-phosphoheptulonate synthase; Function of strongly homologous gene; enzyme.	Histidinol-phosphate aminotransferase; Function of strongly homologous gene; enzyme; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.	0.792
aroF	pheA	NIDE0421	NIDE0419	3-deoxy-7-phosphoheptulonate synthase; Function of strongly homologous gene; enzyme.	P-protein, bifunctional chorismate mutase/prephenate dehydratase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.	0.992
aroF	tyrA	NIDE0421	NIDE0422	3-deoxy-7-phosphoheptulonate synthase; Function of strongly homologous gene; enzyme.	Prephenate dehydrogenase; Function of strongly homologous gene; enzyme.	0.848