node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
NIDE0445 | aroE | NIDE0445 | NIDE0446 | Short-chain dehydrogenase; Function of strongly homologous gene; enzyme. | Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | 0.717 |
NIDE0445 | aroK | NIDE0445 | NIDE0447 | Short-chain dehydrogenase; Function of strongly homologous gene; enzyme. | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. | 0.629 |
NIDE0445 | trmI | NIDE0445 | NIDE0444 | Short-chain dehydrogenase; Function of strongly homologous gene; enzyme. | tRNA (adenine-N(1)-)-methyltransferase; Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA. | 0.827 |
NIDE1522 | trmI | NIDE1522 | NIDE0444 | Putative Beta-phosphoglucomutase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | tRNA (adenine-N(1)-)-methyltransferase; Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA. | 0.609 |
NIDE3396 | trmI | NIDE3396 | NIDE0444 | Putative PP-loop ATPase, YdaO type; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the TtcA family. | tRNA (adenine-N(1)-)-methyltransferase; Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA. | 0.857 |
NIDE3639 | trmI | NIDE3639 | NIDE0444 | Conserved protein of unknown function, ATP-binding; Homologs of previously reported genes of unknown function; 14681586, 9628345. | tRNA (adenine-N(1)-)-methyltransferase; Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA. | 0.565 |
aroE | NIDE0445 | NIDE0446 | NIDE0445 | Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | Short-chain dehydrogenase; Function of strongly homologous gene; enzyme. | 0.717 |
aroE | aroK | NIDE0446 | NIDE0447 | Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. | 0.999 |
aroE | trmI | NIDE0446 | NIDE0444 | Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | tRNA (adenine-N(1)-)-methyltransferase; Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA. | 0.707 |
aroK | NIDE0445 | NIDE0447 | NIDE0445 | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. | Short-chain dehydrogenase; Function of strongly homologous gene; enzyme. | 0.629 |
aroK | aroE | NIDE0447 | NIDE0446 | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. | Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | 0.999 |
aroK | trmI | NIDE0447 | NIDE0444 | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. | tRNA (adenine-N(1)-)-methyltransferase; Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA. | 0.608 |
ksgA | rpmD | NIDE0538 | NIDE1329 | Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. | 50S ribosomal protein L30; Function of homologous gene experimentally demonstrated in an other organism; structure. | 0.703 |
ksgA | trmI | NIDE0538 | NIDE0444 | Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. | tRNA (adenine-N(1)-)-methyltransferase; Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA. | 0.544 |
ksgA | truB | NIDE0538 | NIDE4130 | Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. | tRNA pseudouridine synthase B; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily. | 0.577 |
pan | trmI | NIDE3058 | NIDE0444 | Proteasome-associated ATPase; Function of strongly homologous gene; enzyme; Belongs to the AAA ATPase family. | tRNA (adenine-N(1)-)-methyltransferase; Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA. | 0.535 |
rpmD | ksgA | NIDE1329 | NIDE0538 | 50S ribosomal protein L30; Function of homologous gene experimentally demonstrated in an other organism; structure. | Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. | 0.703 |
rpmD | trmI | NIDE1329 | NIDE0444 | 50S ribosomal protein L30; Function of homologous gene experimentally demonstrated in an other organism; structure. | tRNA (adenine-N(1)-)-methyltransferase; Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA. | 0.745 |
rpmD | truB | NIDE1329 | NIDE4130 | 50S ribosomal protein L30; Function of homologous gene experimentally demonstrated in an other organism; structure. | tRNA pseudouridine synthase B; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily. | 0.727 |
trmI | NIDE0445 | NIDE0444 | NIDE0445 | tRNA (adenine-N(1)-)-methyltransferase; Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA. | Short-chain dehydrogenase; Function of strongly homologous gene; enzyme. | 0.827 |