Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
pal-2Exported protein of unknown function, OmpA family; No homology to any previously reported sequences; 11173492, 16475801, 17052729, 2202726; Belongs to the Pal lipoprotein family. (236 aa)    
Predicted Functional Partners:
tolB
Protein TolB precursor; Function of homologous gene experimentally demonstrated in an other organism; transporter.
 
 
 0.823
tolQ
Protein TolQ; Function of homologous gene experimentally demonstrated in an other organism; transporter.
 
   
 0.739
macA
Efflux transporter, RND family, MFP subunit, putative Macrolide-specific efflux protein; Function of strongly homologous gene; transporter; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
      
 0.732
NIDE3044
Putative Outer membrane protein assembly factor YaeT precursor; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor.
  
 
 0.693
macB
ABC transporter, ATPase component, putative Macrolide export ATP-binding protein; Function of strongly homologous gene; enzyme.
    
 
 0.662
NIDE3357
Putative Tol-Pal system protein YbgF; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative structure.
 
  
 0.637
tolR
Protein TolR; Function of homologous gene experimentally demonstrated in an other organism; transporter.
 
 
 
 0.620
oxaA
Inner-membrane protein insertion factor OxaA; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.
  
   
 0.617
secG
Preprotein translocase, membrane subunit SecG; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family.
  
   
 0.580
lolC
Lipoprotein-releasing system, transmembrane protein LolC; Function of homologous gene experimentally demonstrated in an other organism; transporter.
  
 
   0.560
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
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