Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
NIDE0498Putative DNA recombination protein RmuC; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; cell process. (471 aa)    
Predicted Functional Partners:
NIDE0499
Homologs of previously reported genes of unknown function.
       0.817
NIDE0500
Protein of unknown function; No homology to any previously reported sequences.
       0.799
pyrF
Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily.
 
      0.561
NIDE0497
Putative Phosphoenolpyruvate synthase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
       0.530
NIDE0495
Exported protein of unknown function, contains Transglycosylase SLT domain; No homology to any previously reported sequences; 14625683, 8203016.
       0.509
ttuD
Putative Hydroxypyruvate reductase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
       0.504
mutL
DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
  
  
 0.457
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
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