Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
yfdZAminotransferase, probable Transaminase MtnE; Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL- diaminopimelate; Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. (391 aa)    
Predicted Functional Partners:
dapF
Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan.
  
 0.917
dapB
Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family.
    
 0.914
glnA
Glutamine synthetase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
   
 
 0.692
folK
2-amino-4-hydroxy-6- hydroxymethyldihydropteridinediphosphokinase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
     
 0.629
panC
Pantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family.
       0.627
NIDE0504
Acyltransferase, family 3; Function of strongly homologous gene; enzyme.
       0.524
pheA
P-protein, bifunctional chorismate mutase/prephenate dehydratase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
  
 0.514
gltB
Glutamate synthase, alpha subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
  
  
 0.492
cheV
Chemotaxis signal transducer CheV; Function of strongly homologous gene; regulator.
      
 0.424
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
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