Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
NIDE0505Conserved protein of unknown function, DUF1499; Homologs of previously reported genes of unknown function. (119 aa)    
Predicted Functional Partners:
NIDE1145
Conserved membrane protein of unknown function, DedA family; Homologs of previously reported genes of unknown function.
 
     0.712
NIDE1146
Putative Mercuric reductase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
 
     0.605
NIDE3565
Putative Ferredoxin-thioredoxin reductase, catalytic subunit; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
  
    0.579
NIDE0506
Protein of unknown function; No homology to any previously reported sequences.
       0.538
NIDE3579
Homologs of previously reported genes of unknown function.
 
     0.536
NIDE3577
Glycosyl transferase, family 2; Function of strongly homologous gene; enzyme.
  
     0.491
NIDE0504
Acyltransferase, family 3; Function of strongly homologous gene; enzyme.
       0.462
NIDE3169
Putative Bacterioferritin; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative carrier.
  
     0.451
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
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