Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
NIDE0528Homologs of previously reported genes of unknown function. (414 aa)    
Predicted Functional Partners:
NIDE0529
Putative Dimethylargininase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
  
  0.998
putA
Bifunctional protein PutA; Function of strongly homologous gene; enzyme; Belongs to the aldehyde dehydrogenase family.
 
  
 0.949
proC
Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
     
  0.900
proC-2
Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
     
  0.900
truD
tRNA pseudouridine synthase D; Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs; Belongs to the pseudouridine synthase TruD family.
 
     0.669
NIDE1198
Protein of unknown function, contains HEAT-like repeats; No homology to any previously reported sequences; 8132596, 9882677, 9989501.
  
     0.452
NIDE0256
Protein of unknown function, HEAT repeat protein; No homology to any previously reported sequences.
  
     0.448
NIDE0525
Putative Metallophosphoesterase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
       0.415
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
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