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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NIDE0534Conserved protein of unknown function, UPF0272; Homologs of previously reported genes of unknown function; Belongs to the LarC family. (402 aa)    
Predicted Functional Partners:
NIDE3731
Conserved protein of unknown function, PP-loop superfamily; Homologs of previously reported genes of unknown function; 7731953.
  
 0.986
NIDE0532
Conserved protein of unknown function, putative NCAIR mutase; Homologs of previously reported genes of unknown function; 10574791.
 
  
 0.922
NIDE0743
Protein of unknown function; No homology to any previously reported sequences.
 
  
 0.861
NIDE0535
Ca2+/Na+ antiporter; Function of strongly homologous gene; transporter.
  
    0.694
pdxA
4-hydroxythreonine-4-phosphate dehydrogenase; Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L- threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).
       0.687
pyrG
CTP synthetase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
 
      0.676
NIDE0537
Protein of unknown function; No homology to any previously reported sequences.
       0.651
ksgA
Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.
       0.623
NIDE0533
Exported protein of unknown function; No homology to any previously reported sequences.
       0.599
NIDE2196
Protein of unknown function, DUF362; No homology to any previously reported sequences.
 
     0.584
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
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