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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NIDE0561Radical SAM superfamily protein, putative Coenzyme PQQ synthesis protein E; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (467 aa)    
Predicted Functional Partners:
hemH
Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family.
   
 
 0.975
NIDE2242
Homologs of previously reported genes of unknown function.
  
  
0.941
NIDE0562
Putative Universal stress protein UspA (modular protein); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor.
 
     0.848
hemY
Protoporphyrinogen oxidase; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX.
     
 0.752
hemD
Porphyrin biosynthesis protein HemD; Function of strongly homologous gene; enzyme.
  
 0.647
NIDE0560
Membrane protein of unknown function; No homology to any previously reported sequences.
       0.597
cobA/hemD
Uroporphyrinogen-III C-methyltransferase and Uroporphyrinogen-III synthase (modular protein); Function of strongly homologous gene; enzyme; Belongs to the precorrin methyltransferase family.
  
 0.582
NIDE4176
Putative Uroporphyrinogen III synthase HemD; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
  
  
 0.516
NIDE0206
Protein of unknown function, CbiX domain; No homology to any previously reported sequences; 11215515, 12055304, 12686546, 12869542, 16042605, 16835730.
  
  
 0.510
forE
2-oxoglutarate:ferredoxin oxidoreductase epsilon subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
      
 0.499
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
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