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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NIDE0597Putative Lactoylglutathione lyase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (132 aa)    
Predicted Functional Partners:
NIDE4281
Putative Hydrolase with N-terminal DNA-binding domain; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
  
  
 0.933
NIDE3370
Putative Hydrolase, beta-lactamase-like; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
     
 0.904
trpB
Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
   
  0.814
trpA
Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.
     
  0.800
dapF
Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan.
       0.580
NIDE0598
Putative N-acetyltransferase, GCN5-related; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
  
    0.563
NIDE0599
Putative Polysaccharide deacetylase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
       0.561
NIDE1759
Homologs of previously reported genes of unknown function.
 
    0.545
nuoCD
NADH-quinone oxidoreductase, subunits C and D; Function of homologous gene experimentally demonstrated in an other organism; enzyme; In the N-terminal section; belongs to the complex I 30 kDa subunit family.
  
  
 0.521
nuoI
NADH-quinone oxidoreductase, subunit I (modular protein); NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
  
  
 0.489
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
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