Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
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NIDE0600Putative Membrane-associated zinc metallopeptidase containing CBS domain pair; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the peptidase M50B family. (389 aa)    
Predicted Functional Partners:
NIDE0598
Putative N-acetyltransferase, GCN5-related; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
       0.651
NIDE0599
Putative Polysaccharide deacetylase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
       0.639
ribBA
Riboflavin biosynthesis protein RibBA; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.
  
 
 0.634
guaA
GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.
  
  
 0.599
NIDE3847
Putative DNA-directed DNA polymerase, family X, modulated with phosphoesterase domain; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
 
    0.515
NIDE3860
Putative Phosphoribosyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
 
    0.478
flaG
Flagellar protein FlaG; Function of strongly homologous gene; structure.
    
   0.470
NIDE3786
Putative Calcium-transporting ATPase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter.
 
    0.458
NIDE3745
Cation-transporting ATPase; Function of strongly homologous gene; transporter.
 
    0.450
mgtA
Magnesium-transporting ATPase, P-type; Function of homologous gene experimentally demonstrated in an other organism; transporter.
 
    0.436
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
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