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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NIDE0600Putative Membrane-associated zinc metallopeptidase containing CBS domain pair; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the peptidase M50B family. (389 aa)    
Predicted Functional Partners:
rfbE
CDP-tyvelose epimerase; Function of strongly homologous gene; enzyme.
  
  
 0.698
rfbB-2
dTDP-glucose 4,6-dehydratase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.
  
  
 0.698
NIDE0598
Putative N-acetyltransferase, GCN5-related; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
       0.661
ribBA
Riboflavin biosynthesis protein RibBA; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.
  
 
 0.647
NIDE0599
Putative Polysaccharide deacetylase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
       0.641
guaA
GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.
  
  
 0.616
flaG
Flagellar protein FlaG; Function of strongly homologous gene; structure.
    
   0.540
NIDE2410
Putative Oxidoreductase, alcohol dehydrogenase-like protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
  
    0.527
NIDE3413
Conserved protein of unknown function, NAD-binding; Homologs of previously reported genes of unknown function.
  
    0.500
NIDE3847
Putative DNA-directed DNA polymerase, family X, modulated with phosphoesterase domain; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
 
    0.495
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
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