Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
NIDE0624Protein of unknown function, containing TPR repeats; No homology to any previously reported sequences; 14659697, 1882418, 7667876, 9482716. (399 aa)    
Predicted Functional Partners:
NIDE1061
Conserved protein of unknown function, contains TPR repeats; Homologs of previously reported genes of unknown function.
  
     0.762
NIDE3673
Protein of unknown function, contains TPR repeats; No homology to any previously reported sequences; 15451670, 1882418, 7667876, 9482716.
 
 
 0.713
NIDE0308
Protein of unknown function, contains Ankyrin and Tetratricopeptide repeats; No homology to any previously reported sequences; 14659697, 7667876, 8108379, 9482716.
 
     0.673
NIDE3440
Conserved protein of unknown function, TPR-like; Homologs of previously reported genes of unknown function; 15223324, 1882418, 7667876, 8722778, 9482716.
 
 
0.537
secA
Preprotein translocase subunit SecA; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane; Belongs to the SecA family.
       0.530
NIDE0625
Exported protein of unknown function; No homology to any previously reported sequences.
       0.529
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
    0.508
NIDE2405
Conserved protein of unknown function, TPR-like; Homologs of previously reported genes of unknown function; 14659697, 15361863, 16893176, 7667876, 9482716.
 
 
 
0.494
NIDE0282
Protein of unknown function, TPR-like; No homology to any previously reported sequences.
  
     0.486
NIDE0815
Putative Hybrid histidine kinase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
 
   
 0.477
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
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