close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NIDE0645Conserved membrane protein of unknown function, containing PepSY-associated TM helices; Homologs of previously reported genes of unknown function. (434 aa)    
Predicted Functional Partners:
NIDE0644
TonB-dependent siderophore receptor; Function of homologous gene experimentally demonstrated in an other organism; transporter.
 
   
 0.928
NIDE0659
TonB-dependent siderophore receptor; Function of strongly homologous gene; receptor.
 
  
 0.793
exbB
Biopolymer transport protein exbB; Function of strongly homologous gene; transporter.
  
    0.784
exbD
Biopolymer transport protein exbD; Function of strongly homologous gene; transporter.
       0.777
NIDE2183
Putative Ferric iron uptake protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter.
 
  
 0.761
fhuA
Ferrichrome iron receptor; Function of homologous gene experimentally demonstrated in an other organism; transporter.
 
  
 0.751
fecR2
Protein FecR, ferric citrate sensor; Function of strongly homologous gene; regulator.
 
     0.741
fecR
Protein FecR, ferric citrate sensor; Function of strongly homologous gene; regulator.
 
     0.729
NIDE2179
Putative Protein FecR, ferric citrate sensor; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator.
 
     0.729
NIDE3525
Putative Iron dicitrate transmembrane sensor FecR; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; regulator.
 
     0.727
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
Server load: low (22%) [HD]