close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
vapCPutative PilT-like protein, containing PIN domain; Toxic component of a toxin-antitoxin (TA) system. An RNase. Belongs to the PINc/VapC protein family. (135 aa)    
Predicted Functional Partners:
NIDE4393
Conserved protein of unknown function, contains Ribbon-helix-helix domain; Homologs of previously reported genes of unknown function; 16528102, 1943695, 9927650.
   
 
 0.869
NIDE1177
Conserved protein of unknown function, putative Prevent-host-death protein; Antitoxin component of a type II toxin-antitoxin (TA) system.
   
 
 0.840
NIDE0652
Homologs of previously reported genes of unknown function; 1943695, 9927650.
       0.777
NIDE0285
Conserved protein of unknown function, DUF132; Homologs of previously reported genes of unknown function.
  
   
 0.575
NIDE0653
Protein of unknown function; No homology to any previously reported sequences.
       0.496
NIDE3671
Restriction endonuclease, type II; Function of strongly homologous gene; enzyme.
  
     0.439
NIDE3688
Putative Antitoxin YefM; Antitoxin component of a type II toxin-antitoxin (TA) system.
 
   
 0.432
NIDE2379
Homologs of previously reported genes of unknown function.
  
   
 0.421
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.