STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
hlyDSecretion protein HlyD; Function of strongly homologous gene; transporter; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. (422 aa)    
Predicted Functional Partners:
NIDE0666
ABC-type transport system, permease component; Function of strongly homologous gene; transporter.
 
   0.947
NIDE0667
ABC-type transport system, permease component; Function of strongly homologous gene; transporter.
 
   0.936
ybbA-2
ABC-type transport system, ATPase component; Function of strongly homologous gene; transporter.
 
   0.933
hlyB
Type I secretion system ATPase HlyB; Function of strongly homologous gene; transporter.
   
  
 0.800
smbP
Metal-binding protein SmbP; Function of homologous gene experimentally demonstrated in an other organism; factor.
      
 0.795
secA-2
Protein translocase, subunit SecA; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
      
 0.733
gcvT
Aminomethyltransferase, glycine cleavage system T protein; The glycine cleavage system catalyzes the degradation of glycine.
      
 0.732
NIDE3323
Putative Membrane-fusion protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter.
  
  
  0.712
NIDE3198
Putative Outer membrane efflux protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter.
  
  0.687
NIDE1685
Putative Outer membrane protein TolC precursor; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter.
  
  0.686
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.