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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hlyDSecretion protein HlyD; Function of strongly homologous gene; transporter; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. (422 aa)    
Predicted Functional Partners:
NIDE0666
ABC-type transport system, permease component; Function of strongly homologous gene; transporter.
 
   0.948
ybbA-2
ABC-type transport system, ATPase component; Function of strongly homologous gene; transporter.
 
   0.942
NIDE0667
ABC-type transport system, permease component; Function of strongly homologous gene; transporter.
 
   0.938
hlyB
Type I secretion system ATPase HlyB; Function of strongly homologous gene; transporter.
   
  
 0.754
smbP
Metal-binding protein SmbP; Function of homologous gene experimentally demonstrated in an other organism; factor.
      
 0.742
gcvT
Aminomethyltransferase, glycine cleavage system T protein; The glycine cleavage system catalyzes the degradation of glycine.
      
 0.697
secA-2
Protein translocase, subunit SecA; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
      
 0.694
leuS
Leucyl-tRNA synthetase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the class-I aminoacyl-tRNA synthetase family.
      
 0.690
yajC
Preprotein translocase, subunit YajC; Function of homologous gene experimentally demonstrated in an other organism; membrane component.
      
 0.660
secD
Protein-export membrane protein SecD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.
      
 0.657
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
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