Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ybbA-2ABC-type transport system, ATPase component; Function of strongly homologous gene; transporter. (232 aa)    
Predicted Functional Partners:
macC
ABC transporter, permease component, putative Macrolide export permease protein; Function of strongly homologous gene; transporter.
 
 0.979
NIDE3944
Putative ABC-type transport system, permease component; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter.
 
 0.979
NIDE0666
ABC-type transport system, permease component; Function of strongly homologous gene; transporter.
 
 0.973
NIDE0667
ABC-type transport system, permease component; Function of strongly homologous gene; transporter.
 
 
 0.965
hlyD
Secretion protein HlyD; Function of strongly homologous gene; transporter; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
   0.933
NIDE1279
ABC-type transport system, ATPase component; Function of strongly homologous gene; enzyme.
 
   
0.909
pstB
Phosphate ABC transporter, ATP-binding protein; Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.
  
0.806
modB
Molybdate ABC transporter, permease protein; Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
    
 0.642
lolC
Lipoprotein-releasing system, transmembrane protein LolC; Function of homologous gene experimentally demonstrated in an other organism; transporter.
 
 0.633
NIDE2672
Putative Vitamin B12 import system, ATP-binding protein BtuD; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
 
   
0.606
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
Server load: low (16%) [HD]