Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
copACopper-exporting ATPase; Function of strongly homologous gene; transporter. (960 aa)    
Predicted Functional Partners:
merP
Periplasmic mercury ion binding protein; Involved in mercury resistance. Acts as a mercury scavenger that specifically binds to a mercuric ion in the periplasm and probably passes it to the cytoplasmic mercuric reductase MerA via the mercuric transport protein MerT.
 
 
 0.970
NIDE2642
Putative Permease, YjgP/YjgQ family; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter.
      
 0.803
NIDE2643
Putative Permease, YjgP/YjgQ family; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter.
      
 0.803
pilT1
Twitching mobility protein PilT; Function of homologous gene experimentally demonstrated in an other organism; structure.
      
 0.803
nirK
Copper-containing nitrite reductase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
  
 0.743
NIDE2534
Putative Copper-containing nitrite reductase (NO-forming); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme.
  
 0.727
NIDE0677
Putative Disulfide oxidoreductase dsbA; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
   
 
 0.623
NIDE0679
Protein of unknown function; No homology to any previously reported sequences.
       0.594
czcA
Cation efflux system protein CzcA; Function of strongly homologous gene; transporter; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
   
 0.532
NIDE1587
Protein of unknown function, putative Sensory histidine kinase with methyltransferase region; No homology to any previously reported sequences; 11369279, 11489844, 15009198, 16176121, 16622408, 18076326, 7699720, 9301332, 9382818.
  
  
 0.503
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
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