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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NIDE0727Putative Acriflavine resistance protein acrA; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. (412 aa)    
Predicted Functional Partners:
acrB
Acriflavin resistance protein acrB; Function of strongly homologous gene; transporter; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
   0.928
NIDE0728
Putative Transcriptional regulator acrR; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator.
     
 0.805
acrB2
RND-type permease AcrB; Function of strongly homologous gene; transporter; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
 
   0.803
NIDE2163
Putative Multidrug efflux transporter; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
 
   0.797
macC
ABC transporter, permease component, putative Macrolide export permease protein; Function of strongly homologous gene; transporter.
 
 0.732
NIDE3944
Putative ABC-type transport system, permease component; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter.
 
 0.731
NIDE3493
Putative RND efflux system, multidrug resistance protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
 
   0.715
macB
ABC transporter, ATPase component, putative Macrolide export ATP-binding protein; Function of strongly homologous gene; enzyme.
 
   0.665
NIDE1804
Heavy metal efflux pump, CzcA family, putative Acriflavine resistance protein B; Function of strongly homologous gene; transporter; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
 
 0.651
ttgB
RND efflux system, multidrug resistance protein; Function of strongly homologous gene; transporter; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
 
   0.646
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
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