Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
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NIDE0727Putative Acriflavine resistance protein acrA; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. (412 aa)    
Predicted Functional Partners:
acrB
Acriflavin resistance protein acrB; Function of strongly homologous gene; transporter; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
  0.984
acrB2
RND-type permease AcrB; Function of strongly homologous gene; transporter; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
 
  0.957
NIDE2163
Putative Multidrug efflux transporter; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
 
  0.956
NIDE3493
Putative RND efflux system, multidrug resistance protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
  
  0.939
ttgB
RND efflux system, multidrug resistance protein; Function of strongly homologous gene; transporter; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
  
  0.924
NIDE3916
RND-type efflux transporter, transmembrane pump; Function of strongly homologous gene; transporter; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
  
  0.880
NIDE0728
Putative Transcriptional regulator acrR; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator.
     
 0.795
NIDE3915
Putative Outer membrane efflux protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter.
  
  0.787
NIDE3198
Putative Outer membrane efflux protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter.
  
  0.772
NIDE1685
Putative Outer membrane protein TolC precursor; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter.
  
  0.757
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
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