close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NIDE0728Putative Transcriptional regulator acrR; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator. (215 aa)    
Predicted Functional Partners:
NIDE0727
Putative Acriflavine resistance protein acrA; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
     
 0.805
acrB
Acriflavin resistance protein acrB; Function of strongly homologous gene; transporter; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
     
 0.605
pth
Aminoacyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family.
  
    0.589
NIDE3826
Putative CoA-substrate-specific enzyme activase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator.
     
 0.528
NIDE0730
Exported protein of unknown function; No homology to any previously reported sequences.
       0.500
NIDE0731
Exported protein of unknown function; No homology to any previously reported sequences.
       0.500
NIDE1185
Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
     
 0.468
NIDE3330
Conserved protein of unknown function, SDR family; Homologs of previously reported genes of unknown function; 7742302.
 
   
 0.455
NIDE1742
Putative Multi-domain non-ribosomal peptide synthetase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
     
 0.410
NIDE0805
Putative Hybrid histidine kinase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
    
 
 0.407
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.