STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
comDSulfopyruvate decarboxylase, alpha subunit; Function of strongly homologous gene; enzyme. (165 aa)    
Predicted Functional Partners:
comE
Sulfopyruvate decarboxylase, beta subunit; Function of strongly homologous gene; enzyme.
  
  0.999
NIDE2903
Putative Phosphoenolpyruvate phosphomutase (modular protein); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
   
 0.885
NIDE0735
Putative Sugar nucleotidyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
 
     0.809
NIDE3208
Protein of unknown function; No homology to any previously reported sequences.
   
    0.802
phnW
2-aminoethylphosphonate aminotransferase; Function of strongly homologous gene; enzyme.
 
   
 0.772
NIDE0737
Homologs of previously reported genes of unknown function.
 
     0.757
NIDE0387
Protein of unknown function; No homology to any previously reported sequences.
   
    0.744
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
   
    0.744
napG
Ferredoxin-type protein NapG; Function of strongly homologous gene; enzyme.
   
    0.645
NIDE0731
Exported protein of unknown function; No homology to any previously reported sequences.
       0.558
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.