STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
phnW2-aminoethylphosphonate aminotransferase; Function of strongly homologous gene; enzyme. (366 aa)    
Predicted Functional Partners:
ppd
Phosphonopyruvate decarboxylase; Function of strongly homologous gene; enzyme.
 
 
 0.950
NIDE0735
Putative Sugar nucleotidyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
 
    0.897
comE
Sulfopyruvate decarboxylase, beta subunit; Function of strongly homologous gene; enzyme.
 
 
 0.804
trpE
Anthranilate synthase, component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concent [...]
      
 0.795
suhB
Inositol-phosphate phosphatase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the inositol monophosphatase superfamily.
      
 0.793
comD
Sulfopyruvate decarboxylase, alpha subunit; Function of strongly homologous gene; enzyme.
 
   
 0.772
atpD
ATP synthase F1, beta subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.
   
  
 0.761
trpD
Anthranilate phosphoribosyltransferase; Function of strongly homologous gene; enzyme.
      
 0.759
trpD-2
Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA).
      
 0.759
NIDE3330
Conserved protein of unknown function, SDR family; Homologs of previously reported genes of unknown function; 7742302.
 
 0.744
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.