STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NIDE0737Homologs of previously reported genes of unknown function. (331 aa)    
Predicted Functional Partners:
NIDE0736
Putative sugar nucleotidyltransferase and phosphatidyltransferase (bifunctional enzyme); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
 
  
 0.912
comD
Sulfopyruvate decarboxylase, alpha subunit; Function of strongly homologous gene; enzyme.
 
     0.757
comE
Sulfopyruvate decarboxylase, beta subunit; Function of strongly homologous gene; enzyme.
 
    0.737
NIDE0700
Putative Dihydroflavanol 4-reductase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
 
     0.736
shc
Squalene-hopene cyclase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
     0.720
NIDE0735
Putative Sugar nucleotidyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
 
     0.709
NIDE0891
Radical SAM protein; Function of strongly homologous gene; enzyme.
 
     0.662
phnW
2-aminoethylphosphonate aminotransferase; Function of strongly homologous gene; enzyme.
 
     0.647
NIDE2903
Putative Phosphoenolpyruvate phosphomutase (modular protein); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
 
   
 0.636
NIDE0307
Conserved membrane protein of unknown function, DUF898; Homologs of previously reported genes of unknown function.
  
     0.512
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
Server load: low (18%) [HD]