Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
NIDE0773Putative Esterase, beta-lactamase family; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (375 aa)    
Predicted Functional Partners:
nagZ
Beta-N-acetylglucosaminidase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
  
 0.976
ftsI
Peptidoglycan glycosyltransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
    
 0.925
mtgA
Monofunctional biosynthetic peptidoglycan transglycosylase; Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors; Belongs to the glycosyltransferase 51 family.
   
 
 0.919
NIDE0434
Putative D-alanyl-D-alanine carboxypeptidase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the peptidase S11 family.
     
 0.916
mrdA
Penicillin-binding protein 2; Function of strongly homologous gene; enzyme.
     
 0.914
NIDE3591
Putative Penicillin-binding protein 1B; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
     
 0.912
mrcA
Penicillin-binding protein 1A; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
     
 0.912
proC
Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
     
 0.621
NIDE0772
Putative Cell division protein DivIVA; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor.
     
 0.611
yggS
Conserved protein of unknown function, UPF0001; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
       0.573
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
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