STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pilRTranscriptional regulatory protein pilR; Function of strongly homologous gene; regulator. (459 aa)    
Predicted Functional Partners:
NIDE0778
Putative Sensor protein PilS; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
 
 
  0.991
rpoN
RNA polymerase, sigma-54 (sigma N) factor; Function of homologous gene experimentally demonstrated in an other organism; factor.
 
  
 0.946
pilC
Type IV pilus biogenesis protein PilC; Function of strongly homologous gene; transporter.
     
 0.923
pilA2
Type IV pilin PilA; Function of homologous gene experimentally demonstrated in an other organism; structure.
      
 0.795
ispE
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
       0.772
pstS
Phosphate ABC transporter, periplasmic phosphate-binding protein; Function of homologous gene experimentally demonstrated in an other organism; transporter.
      
 0.731
ATPase
ATPase, AAA family; Function of strongly homologous gene; enzyme.
      
 0.627
yefM
Antitoxin of toxin-antitoxin stability system; Antitoxin component of a type II toxin-antitoxin (TA) system.
      
 0.627
yefM-2
Addiction module antitoxin yefM; Antitoxin component of a type II toxin-antitoxin (TA) system.
      
 0.627
NIDE4272
Putative Sensor histidine kinase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
 
 
   0.547
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.