STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
forD2-oxoglutarate:ferredoxin oxidoredutase delta subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (254 aa)    
Predicted Functional Partners:
pstA
Phosphate ABC transporter, auxiliary and permease protein (modular protein); Function of strongly homologous gene; transporter.
  
 
 0.870
forE
2-oxoglutarate:ferredoxin oxidoreductase epsilon subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
       0.762
pstB
Phosphate ABC transporter, ATP-binding protein; Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.
  
 
 0.758
forC
2-oxoglutarate:ferredoxin oxidoredutase gamma subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
     
 0.727
forA
2-oxoglutarate:ferredoxin oxidoredutase alpha subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
     
 0.723
forB
2-oxoglutarate:ferredoxin oxidoredutase beta subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
     
 0.662
sucD
Succinyl-CoA synthetase, NAD(P)-binding, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
   
 
  0.516
sucC
Succinyl-CoA synthetase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
   
 
  0.512
idh
Isocitrate dehydrogenase (NADP(+)); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the monomeric-type IDH family.
     
  0.500
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.