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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NIDE0832Protein of unknown function, putative Protein tyrosine phosphatase; No homology to any previously reported sequences; 14739250, 1650499, 2550140, 8987394, 9646865, 9818190. (140 aa)    
Predicted Functional Partners:
NIDE1523
Protein of unknown function; No homology to any previously reported sequences; 14731533, 15335710, 1639195, 7531822, 7953536.
   
 0.759
NIDE3282
Exported protein of unknown function, contains WD40 repeats; No homology to any previously reported sequences; 1909108.
   
 0.759
lepA
GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner.
    
  0.667
NIDE0831
Protein of unknown function; No homology to any previously reported sequences.
       0.624
NIDE3861
Homologs of previously reported genes of unknown function.
  
 
 0.584
mutM
DNA-formamidopyrimidine glycosylase and DNA-(apurinic or apyrimidinic site) lyase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
       0.557
NIDE0830
Protein of unknown function; No homology to any previously reported sequences.
       0.530
NIDE2880
Glycosyl transferase, group 1; Function of strongly homologous gene; enzyme.
  
 
  0.465
NIDE0308
Protein of unknown function, contains Ankyrin and Tetratricopeptide repeats; No homology to any previously reported sequences; 14659697, 7667876, 8108379, 9482716.
   
 0.463
yahD
Conserved protein of unknown function, contains Ankyrin repeats; Homologs of previously reported genes of unknown function; 15063798, 8108379.
   
 0.460
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.