STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NIDE0832Protein of unknown function, putative Protein tyrosine phosphatase; No homology to any previously reported sequences; 14739250, 1650499, 2550140, 8987394, 9646865, 9818190. (140 aa)    
Predicted Functional Partners:
NIDE1523
Protein of unknown function; No homology to any previously reported sequences; 14731533, 15335710, 1639195, 7531822, 7953536.
   
 0.720
NIDE3282
Exported protein of unknown function, contains WD40 repeats; No homology to any previously reported sequences; 1909108.
   
 0.720
NIDE0831
Protein of unknown function; No homology to any previously reported sequences.
       0.622
mutM
DNA-formamidopyrimidine glycosylase and DNA-(apurinic or apyrimidinic site) lyase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
       0.554
NIDE3861
Homologs of previously reported genes of unknown function.
  
 
 0.548
mdh
Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family.
    
 
 0.538
NIDE0830
Protein of unknown function; No homology to any previously reported sequences.
       0.529
NIDE0081
Homologs of previously reported genes of unknown function.
   
 0.517
NIDE0273
Conserved protein of unknown function, small GTP-binding protein; Homologs of previously reported genes of unknown function; 11099382, 12163169, 12384139, 12728271, 17143896.
   
 0.517
NIDE0308
Protein of unknown function, contains Ankyrin and Tetratricopeptide repeats; No homology to any previously reported sequences; 14659697, 7667876, 8108379, 9482716.
   
 0.469
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
Server load: low (26%) [HD]