node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
NIDE3854 | aclA | NIDE3854 | NIDE0835 | Putative Pyruvate dehydrogenase complex, dihydrolipoamide acetyltransferase (E2) component; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | ATP citrate lyase, alpha subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.995 |
NIDE3854 | atoB | NIDE3854 | NIDE3116 | Putative Pyruvate dehydrogenase complex, dihydrolipoamide acetyltransferase (E2) component; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Acetyl-CoA acetyltransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the thiolase-like superfamily. Thiolase family. | 0.914 |
NIDE3854 | nuoCD | NIDE3854 | NIDE0613 | Putative Pyruvate dehydrogenase complex, dihydrolipoamide acetyltransferase (E2) component; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | NADH-quinone oxidoreductase, subunits C and D; Function of homologous gene experimentally demonstrated in an other organism; enzyme; In the N-terminal section; belongs to the complex I 30 kDa subunit family. | 0.766 |
NIDE3854 | pdhC | NIDE3854 | NIDE3951 | Putative Pyruvate dehydrogenase complex, dihydrolipoamide acetyltransferase (E2) component; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Dihydrolipoamide acetyltransferase (E2) component of pyruvate dehydrogenase complex; Function of strongly homologous gene; enzyme. | 0.915 |
NIDE3854 | scpAa | NIDE3854 | NIDE3118 | Putative Pyruvate dehydrogenase complex, dihydrolipoamide acetyltransferase (E2) component; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Methylmalonyl-CoA mutase (N-terminal fragment); Function of strongly homologous gene; enzyme. | 0.806 |
NIDE3854 | sdhA | NIDE3854 | NIDE0310 | Putative Pyruvate dehydrogenase complex, dihydrolipoamide acetyltransferase (E2) component; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Succinate dehydrogenase/fumarate reductase, flavoprotein subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.677 |
NIDE3854 | sdhB | NIDE3854 | NIDE2517 | Putative Pyruvate dehydrogenase complex, dihydrolipoamide acetyltransferase (E2) component; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. | 0.747 |
NIDE3854 | sucC | NIDE3854 | NIDE0840 | Putative Pyruvate dehydrogenase complex, dihydrolipoamide acetyltransferase (E2) component; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Succinyl-CoA synthetase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.919 |
NIDE3854 | sucD | NIDE3854 | NIDE0841 | Putative Pyruvate dehydrogenase complex, dihydrolipoamide acetyltransferase (E2) component; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Succinyl-CoA synthetase, NAD(P)-binding, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.940 |
aclA | NIDE3854 | NIDE0835 | NIDE3854 | ATP citrate lyase, alpha subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | Putative Pyruvate dehydrogenase complex, dihydrolipoamide acetyltransferase (E2) component; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.995 |
aclA | atoB | NIDE0835 | NIDE3116 | ATP citrate lyase, alpha subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | Acetyl-CoA acetyltransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the thiolase-like superfamily. Thiolase family. | 0.924 |
aclA | nuoCD | NIDE0835 | NIDE0613 | ATP citrate lyase, alpha subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | NADH-quinone oxidoreductase, subunits C and D; Function of homologous gene experimentally demonstrated in an other organism; enzyme; In the N-terminal section; belongs to the complex I 30 kDa subunit family. | 0.998 |
aclA | pdhC | NIDE0835 | NIDE3951 | ATP citrate lyase, alpha subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | Dihydrolipoamide acetyltransferase (E2) component of pyruvate dehydrogenase complex; Function of strongly homologous gene; enzyme. | 0.995 |
aclA | scpAa | NIDE0835 | NIDE3118 | ATP citrate lyase, alpha subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | Methylmalonyl-CoA mutase (N-terminal fragment); Function of strongly homologous gene; enzyme. | 0.878 |
aclA | sdhA | NIDE0835 | NIDE0310 | ATP citrate lyase, alpha subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | Succinate dehydrogenase/fumarate reductase, flavoprotein subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.992 |
aclA | sdhB | NIDE0835 | NIDE2517 | ATP citrate lyase, alpha subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. | 0.996 |
aclA | sdhE | NIDE0835 | NIDE2527 | ATP citrate lyase, alpha subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | Succinate dehydrogenase, subunit C; Function of strongly homologous gene; enzyme. | 0.529 |
aclA | sucC | NIDE0835 | NIDE0840 | ATP citrate lyase, alpha subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | Succinyl-CoA synthetase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.999 |
aclA | sucD | NIDE0835 | NIDE0841 | ATP citrate lyase, alpha subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | Succinyl-CoA synthetase, NAD(P)-binding, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.722 |
atoB | NIDE3854 | NIDE3116 | NIDE3854 | Acetyl-CoA acetyltransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the thiolase-like superfamily. Thiolase family. | Putative Pyruvate dehydrogenase complex, dihydrolipoamide acetyltransferase (E2) component; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.914 |