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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NIDE0843Conserved protein of unknown function, containing B12-binding and radical SAM domain; Homologs of previously reported genes of unknown function; 11222759, 14704425, 7992050. (544 aa)    
Predicted Functional Partners:
NIDE2333
Conserved protein of unknown function, Fe-S oxidoreductase; Homologs of previously reported genes of unknown function; 11222759, 11882645, 14527323, 14633981, 14704425, 9242908.
  
  
 
0.929
NIDE2780
Conserved protein of unknown function, putative radical SAM; Homologs of previously reported genes of unknown function; 14633981, 14704425, 15317939.
  
  
 
0.929
NIDE2331
Conserved protein of unknown function, Fe-S oxidoreductase; Homologs of previously reported genes of unknown function; 11222759, 11882645, 14633981, 14704425.
  
  
 
0.928
NIDE0842
Protein of unknown function; No homology to any previously reported sequences.
       0.620
NIDE0852
Geranylgeranyl reductase family protein; Function of strongly homologous gene; enzyme.
 
  
 0.501
sucD
Succinyl-CoA synthetase, NAD(P)-binding, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
       0.449
sucC
Succinyl-CoA synthetase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
       0.438
NIDE0147
Putative Polyphosphate kinase 2; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
   
    0.429
NIDE3880
Conserved protein of unknown function, putative Polyphosphate kinase; Homologs of previously reported genes of unknown function; 12486232.
   
    0.429
NIDE0684
Exported protein of unknown function, MCP-like; No homology to any previously reported sequences.
  
     0.425
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.