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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NIDE0847Putative Cytochrome c biogenesis protein, ResB-like; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (478 aa)    
Predicted Functional Partners:
ccsA
Cytochrome c biogenesis protein CcsA (ResC-like); Function of strongly homologous gene; transporter.
 
  
 0.983
ccdA
Cytochrome c biogenesis protein CcdA; Function of strongly homologous gene; enzyme.
 
  
 0.827
NIDE2746
Putative Cytochrome c biogenesis protein CcsA; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter.
  
     0.773
cobA/hemD
Uroporphyrinogen-III C-methyltransferase and Uroporphyrinogen-III synthase (modular protein); Function of strongly homologous gene; enzyme; Belongs to the precorrin methyltransferase family.
  
    0.768
hemD
Porphyrin biosynthesis protein HemD; Function of strongly homologous gene; enzyme.
  
    0.768
resA-2
Thiol-disulfide oxidoreductase ResA; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
  
  
 0.630
resA2
Thiol-disulfide oxidoreductase ResA; Function of strongly homologous gene; enzyme.
  
  
 0.570
NIDE0616
Homologs of previously reported genes of unknown function.
  
     0.521
atpA
ATP synthase F1, alpha subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.
  
  
 0.464
atpB
ATP synthase F0, subunit A; Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane. Belongs to the ATPase A chain family.
  
  
 0.453
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
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